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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
JNJ-2408068
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| Category | Respiratory syncytial Virus (RSV) |
| CAS | 317846-22-3 |
| Description | JNJ-2408068 is a potent inhibitor of respiratory syncytial virus (RSV), exhibits potent antiviral activity with 50% effective concentrations (EC50s) of 1.4 and 2.1 nM, respectively. |
Product Information
| Synonyms | R170591; R-170591; R 170591; HE066500; HE-066500; HE 066500; JNJ-2408068; JNJ 2408068; JNJ2408068. 2-[[2-[[1-(2-aminoethyl)piperidin-4-yl]amino]-4-methylbenzimidazol-1-yl]methyl]-6-methylpyridin-3-ol; |
| IUPAC Name | 2-[[2-[[1-(2-aminoethyl)piperidin-4-yl]amino]-4-methylbenzimidazol-1-yl]methyl]-6-methylpyridin-3-ol |
| Molecular Weight | 394.52 |
| Molecular Formula | C22H30N6O |
| Canonical SMILES | CC1=C2C(=CC=C1)N(C(=N2)NC3CCN(CC3)CCN)CC4=C(C=CC(=N4)C)O |
| InChI | 1S/C22H30N6O/c1-15-4-3-5-19-21(15)26-22(25-17-8-11-27(12-9-17)13-10-23)28(19)14-18-20(29)7-6-16(2)24-18/h3-7,17,29H,8-14,23H2,1-2H3,(H,25,26) |
| InChIKey | RDQSNNMSDOHAPG-UHFFFAOYSA-N |
| Purity | ≥98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Application | Respiratory syncytial virus inhibitor |
| Shelf Life | As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly. |
| Storage | Store at -20 °C |
| Complexity | 514 |
| Exact Mass | 394.24810960 |
| PSA | 95.46000 |
| Target | RSV |
| XLogP3-AA | 2.4 |
