-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Isoliquiritigenin
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/961-29-5.gif)
| Category | Influenza Virus |
| CAS | 961-29-5 |
| Description | Isoliquiritigenin, a flavonoid from the root of Glycyrrhiza glabrat, inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μm. It has antioxidant, anti-inflammatory, and anti-tumor activities. |
Product Information
| Synonyms | (2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; ISL; 2',4,4'-Trihydroxychalcone; GU 17; 6'-deoxychalcone; 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-; trans-2',4,4'-trihydroxychalcone |
| IUPAC Name | (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one |
| Molecular Weight | 256.25 |
| Molecular Formula | C15H12O4 |
| Canonical SMILES | C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O |
| InChI | InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+ |
| InChIKey | DXDRHHKMWQZJHT-FPYGCLRLSA-N |
| Boiling Point | 504.0±42.0°C (Predicted) |
| Melting Point | >193°C (dec.) |
| Flash Point | 272.7±24.4 °C |
| Purity | >98% |
| Density | 1.384±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Appearance | Yellow powder |
| Application | antidiabetic; antitumour; antioxidant; anti-inflammatory; antimutagenic; antifungal; |
| Storage | Store at 2-8°C |
| Complexity | 331 |
| Exact Mass | 256.07355886 |
| Index Of Refraction | 1.715 |
| PSA | 77.76000 |
| Target | Aldose Reductase; Influenza Virus; Autophagy; Apoptosis |
| Vapor Pressure | 0.0±1.3 mmHg at 25°C |
| XLogP3-AA | 3.2 |
