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Honokiol

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Category	Hepatitis C Virus (HCV)
CAS	35354-74-6
Description	Honokiol is a polyphenol found in the genus Magnolia. Honokiol acts as an Akt inhibitor and also inhibits NF-κB, displaying anti-inflammatory, antiangiogenic and antitumor properties. It results in inhibition of bone metastatic growth of human prostate cancer cells. Honokiol has obvious antioxidant and anti-aging effects, thus can be used in cosmetic material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. It has the activity of antibacterial, anti-inflammatory, antioxidant, oil control, acne, promoting healing, and can be widely used in anti-acne, deodorization, acne and other products.

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Synonyms	Honokiol;35354-74-6;5,3'-Diallyl-2,4'-dihydroxybiphenyl;NSC 293100;3,5'-Diallyl-4,2'-dihydroxybiphenyl;3',5-Diallylbiphenyl-2,4'-diol;C18H18O2;3',5-diallyl-2,4'-biphenyldiol;CPD000387107;CHEMBL16901;2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol;CHEBI:5759;4-allyl-2-(3-allyl-4-hydroxy-phenyl)phenol;11513CCO0N;2-[4-hydroxy-3-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol;5,3'-Diallyl-biphenyl-2,4'-diol;MFCD00016674;NSC293100;[1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propenyl-;3',5-Di-2-propen-1-yl[1,1'-biphenyl]-2,4'-diol;NSC-293100;Honokiol,(S);2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol;(1P)-3',5-di(prop-2-en-1-yl)[1,1'-biphenyl]-2,4'-diol;3',5-(5,5'-)Diallyl-[1,1'-biphenyl]-2,4'-(2,2'-)diol;SMR000387107;3',5-di(prop-2-en-1-yl)biphenyl-2,4'-diol;Purinol;(1,1'-BIPHENYL)-2,4'-DIOL, 3',5-DI-2-PROPENYL-;UNII-11513CCO0N;Honokiol?;-dihydroxydiphenyl;3',5-diallyl-[1,1'-biphenyl]-2,4'-diol;Honokiol, HO;3',5-Di-2-propen-1-yl-[1,1'-biphenyl]-2,4'-diol; [1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propenyl- (9CI); 3',5-Diallyl-2,4'-biphenyldiol; Honokiol; NSC 293100;5,3′Honokiol - 95%;-Diallyl-2,4′FMLT BSASM H;HONOKIOL [MI];HONOKIOL [WHO-DD];Honokiol, analytical standard;cid_72303;MLS000759481;MLS001048916;MLS001423980;MLS006011755;SCHEMBL133034;REGID_for_CID_72303;GTPL11610;DTXSID30188845;3',1'-biphenyl)-2,4'-diol;HMS2051C12;HMS2271J07;HMS3393C12;HMS3656G03;(1,1'-BIPHENYL)-2,4'-DIOL, 3',5-DI-2-PROPEN-1-YL-;AMY40657;BCP28282;HY-N0003;AC-486;BBL027819;BDBM50157304;HB0328;s2310;STK801954;3'',5-diallylbiphenyl-2,4''-diol;Honokiol, >=98% (HPLC), powder;3,5'-diallyl-2',4-dihydroxybiphenyl;AKOS005622639;3',5-Diallyl-2,4'-dihydroxybiphenyl;CCG-100864;CS-1696;NC00114;5,3''-Diallyl-biphenyl-2,4''-diol;SMP2_000040;NCGC00163567-01;NCGC00163567-02;NCGC00163567-03;NCGC00163567-08;AS-15333;XH163752;5,3''''-Diallyl-biphenyl-2,4''''-diol;H1309;NS00011726;SW197494-3;EN300-7399522;A822747;SR-01000758208;Q-100425;Q5896650;SR-01000758208-5;{1,1'-Biphenyl]-2,4'-diol, 3,5-di-2-propenyl-;3'',5-di-2-propenyl-1,1''-biphenyl-2,4''-diol;BRD-K98493452-001-01-6;BRD-K98493452-001-14-9;Honokiol, European Pharmacopoeia (EP) Reference Standard;Z2065671480;[1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propen-1-yl;4-[2-hydroxy-5-(prop-2-en-1-yl)phenyl]-2-(prop-2-en-1-yl)phenol;InChI=1/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H;N-[[4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-2-fluoroaniline; N-?(2-?Fluorophenyl)?-?5-?(6-?methyl-?2-?pyridinyl)?-?4-?[1,?2,?4]?triazolo[1,?5-?a]?pyridin-?6-?yl-1H-?imidazole-?2-?methanamine;Y4T;
IUPAC Name	2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol
Molecular Weight	541.6
Molecular Formula	C34H31N5O2
Canonical SMILES	C[C@@H](C1=CC2=CC=CC=C2C=C1)NC(=O)C3=C4C(=CC=C3)N=C(N4CCCC(=O)NC)C5=CN=CC6=CC=CC=C65
InChI	InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
InChIKey	FVYXIJYOAGAUQK-UHFFFAOYSA-N
Boiling Point	400.1°C at 760 mmHg
Melting Point	80-85°C
Flash Point	184°C
Purity	≥98%
Density	1.107 g/cm3
Solubility	Soluble in DMSO (36 mg/mL)
Appearance	White Solid
Application	anti-inflammatory and anti-cancer agent
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

QC Data

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