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HIV-1-protease-IN-7

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Category HIV Integrase
Description HIV-1 protease-IN-7 (compound 16) is an orally active HIV-1 protease inhibitor (IC50=3.52 nM, EC50=37 nM).
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Product Information

Molecular Weight 1285.68
Molecular Formula C68H104N10O12S
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
In Vitro HIV-1 protease-IN-7 (2.57 mg/kg; p.o.; single) exhibits good plasma total clearance and oral bioavailability.
Target IC50: 0.021 nM (HIV-1 protease)
EC50: 0.74 μM (HIV-1 NL4-3), 0.61 μM (HIV DRVRs)

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