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HIV-1-protease-IN-6

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Category HIV Integrase
Description HIV-1 protease-IN-6 (compound 17d) is a potent HIV-1 protease inhibitor, with an IC50 of 21 pM and a Ki of 4.7 pM, respectively. HIV-1 protease-IN-6 exhibits potent antiviral activity to DRV (darunavir)-resistant variant, even more than wild.
type virus
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Product Information

Synonyms HIV-1 protease-IN-6|CS-0534468
Molecular Weight 530.61
Molecular Formula C27H31FN2O6S
Canonical SMILES CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)C2=CC(=CC(=C2)O)O)O)S(=O)(=O)C3=CC=C(C=C3)F
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 798
Exact Mass 530.18868605
Target HIV Protease; HIV
XLogP3-AA 4.2

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