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HIV-1-integrase-inhibitor-9

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Category Human immunodeficiency Virus (HIV)
CAS 2709085-95-8
Description HIV-1 integrase inhibitor 9 (compound 8a) is a potent HIV-1 RNase H inhibitor with an IC50 of 12.3 μM. HIV-1 integrase inhibitor 9 shows an antiviral activity.
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Product Information

Synonyms HIV-1 integrase inhibitor 9|CHEMBL4867922|BDBM50579011|HY-132572|CS-0201133
Molecular Weight 416.3
Molecular Formula C18H12N2O10
Canonical SMILES COC(=O)C1=C(C=CC(=C1)NC(=O)C2=CC3=CC(=C(C(=C3OC2=O)O)O)[N+](=O)[O-])O
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 763
Exact Mass 416.04919458
Target HIV-1 RNase H:12.3 nM (IC50)
XLogP3-AA 2.7

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