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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
HIV-1-inhibitor-44
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| Category | Human immunodeficiency Virus (HIV) |
| Description | HIV-1 inhibitor-44 (compound 11l) is a HIV-1 reverse transcriptase inhibitor. HIV-1 inhibitor-44 shows inhibitory activity against wild-type HIV-1 strain with an EC50 value of 0.209 μM. |
Product Information
| Synonyms | HIV-1 inhibitor-44|CS-0541891 |
| Molecular Weight | 426.53 |
| Molecular Formula | C23H26N2O4S |
| Canonical SMILES | CC1=CC(=CC(=C1)S(=O)C2=C(C(=O)NC(=O)N2COCC3=CC=CC=C3)C(C)C)C |
| Purity | ≥98% (HPLC) |
| Solubility | 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 689 |
| Exact Mass | 426.16132849 |
| In Vitro | HIV-1 inhibitor-44 (compound 11l) displays potent inhibitory activity against WT HIV-1, mutant strains L100I and E138K, with EC50s of 0.21 μM, 0.94 μM, and 1.37 μM, respectively. |
| Target | HIV-1: 0.209 μM (EC50) |
| XLogP3-AA | 3.5 |
