-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
HIV-1-inhibitor-42
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/2459929-46-3.gif)
| Category | Human immunodeficiency Virus (HIV) |
| CAS | 2459929-46-3 |
| Description | HIV-1 inhibitor-42 (compound 5b) is a potent HIV-1 inhibitor, with an IC50 of 0.06 μM. HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase and DNA-dependent DNA polymerase, with IC50 values of 0.518 and 0.072 . |
Product Information
| Synonyms | HIV-1 inhibitor-42|HY-147903|CS-0529936 |
| Molecular Weight | 424.47 |
| Molecular Formula | C22H20N2O5S |
| Canonical SMILES | CCC1=C(N=C(NC1=O)SCC(=O)C2=CC=C(C=C2)O)CC3=CC4=C(C=C3)OCO4 |
| Purity | ≥98% (HPLC) |
| Solubility | 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 729 |
| Exact Mass | 424.10929292 |
| Target | HIV-1:0.06 ± 0.0 μM (IC50) HIV-1 (Y181C):15.510 ± 1 μM (IC50) HIV-1 (K103N):53.045 ± 6 μM (IC50) |
| XLogP3-AA | 3.8 |
