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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
HIV-1-inhibitor-35
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 2416971-32-7 |
| Description | HIV-1 inhibitor-35 (compound 74) is a potent HIV-1 inhibitor with EC50s of 80 nM and 70 nM for LTR and CMV in HEK293 cells, respectively. HIV-1 inhibitor-35 has inhibitory activity against liver cancer cell HepG2 with a CC50 of 40 nM. HIV-1 inhibitor-35 can be used as HIV-1 latency reversing agent. |
Product Information
| Synonyms | HIV-1 inhibitor-35|CHEMBL4777866|HY-147552|CS-0513840 |
| Molecular Weight | 392.69 |
| Molecular Formula | C13H12Cl3N5OS |
| Canonical SMILES | C1CN(CCN1C2=CC(=C(N=C2)Cl)Cl)C(=O)NC3=NC=C(S3)Cl |
| Purity | ≥98% (HPLC) |
| Solubility | 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 426 |
| Exact Mass | 390.982814 |
| Target | HIV |
| XLogP3-AA | 3.5 |
