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HIV-1-inhibitor-35

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Category Human immunodeficiency Virus (HIV)
CAS 2416971-32-7
Description HIV-1 inhibitor-35 (compound 74) is a potent HIV-1 inhibitor with EC50s of 80 nM and 70 nM for LTR and CMV in HEK293 cells, respectively. HIV-1 inhibitor-35 has inhibitory activity against liver cancer cell HepG2 with a CC50 of 40 nM. HIV-1 inhibitor-35 can be used as HIV-1 latency reversing agent.
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Product Information

Synonyms HIV-1 inhibitor-35|CHEMBL4777866|HY-147552|CS-0513840
Molecular Weight 392.69
Molecular Formula C13H12Cl3N5OS
Canonical SMILES C1CN(CCN1C2=CC(=C(N=C2)Cl)Cl)C(=O)NC3=NC=C(S3)Cl
Purity ≥98% (HPLC)
Solubility 10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 426
Exact Mass 390.982814
Target HIV
XLogP3-AA 3.5

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