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HIV-1-inhibitor-34

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Category Human immunodeficiency Virus (HIV)
CAS 2395777-45-2
Description HIV-1 inhibitor-34 (compound 5q) is a potent and selective HIV-1 inhibitor with an EC50 of 6.4 nM for HIV-1 and a CC50 of 16 M in MT-4 cells. HIV-1 inhibitor-34 can be used for researching AIDS.
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Product Information

Synonyms HIV-1 inhibitor-34|CHEMBL4747887|HY-146091|CS-0499299|4-[2-[[1-(1H-indazol-3-ylmethyl)-4-piperidyl]amino]pyrimidin-4-yl]oxy-3,5-dimethyl-benzonitrile
Molecular Weight 453.54
Molecular Formula C26H27N7O
Canonical SMILES CC1=CC(=CC(=C1OC2=NC(=NC=C2)NC3CCN(CC3)CC4=C5C=CC=CC5=NN4)C)C#N
Purity ≥98% (HPLC)
Solubility 10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 693
Exact Mass 453.22770851
Target HIV-1 (WT): 6.4 nM (EC50)
XLogP3-AA 4.6

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