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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
HIV-1-inhibitor-33
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 2395777-43-0 |
| Description | HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor with an EC50 of 8.6 nM for HIV-1 and a CC50 of 18 M in MT-4 cells. HIV-1 inhibitor-33 can be used for researching AIDS. |
Product Information
| Synonyms | HIV-1 inhibitor-33|CHEMBL4760322|HY-146090|CS-0499298|4-(2,6-dimethylphenoxy)-N-[1-(1H-indazol-3-ylmethyl)-4-piperidyl]pyrimidin-2-amine |
| Molecular Weight | 428.53 |
| Molecular Formula | C25H28N6O |
| Canonical SMILES | CC1=C(C(=CC=C1)C)OC2=NC(=NC=C2)NC3CCN(CC3)CC4=C5C=CC=CC5=NN4 |
| Purity | ≥98% (HPLC) |
| Solubility | 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 575 |
| Exact Mass | 428.23245954 |
| Target | HIV-1 (WT): 8.6 nM (EC50) |
| XLogP3-AA | 4.9 |
