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HIV-1-inhibitor-29

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Category Human immunodeficiency Virus (HIV)
CAS 2642217-95-4
Description HIV-1 inhibitor-29 (compound 14d2) is a potent HIV-1 inhibitor with an EC50 of 2.18 μM for HIV-1 IIIB. HIV-1 inhibitor-29 has high anti-resistance profile toward F227L/V106A strain (EC50 = 0.974 μM), and exhibits low cytotoxicity in MT-4 cells (CC50 = 211 μM). HIV-1 inhibitor-29 can be used for researching AIDS.
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Product Information

Synonyms HIV-1 inhibitor-29|CHEMBL4789601|HY-146353|CS-0498453
Molecular Weight 560.64
Molecular Formula C30H36N6O5
Canonical SMILES CC1=CC(=CC(=C1OC2=NC(=NC3=CC(=C(C=C32)OC)OC)NC4CCN(CC4)CC(=O)N5CCOCC5)C)C#N
Purity ≥98% (HPLC)
Solubility 10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 891
Exact Mass 560.27471827
Target HIV (IIIB):2.18 μM (EC50)
HIV-1 (F227L/V106A):0.974 μM (EC50)
XLogP3-AA 3.9

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