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HIV-1-inhibitor-26

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Category Human immunodeficiency Virus (HIV)
CAS 2415504-88-8
Description HIV-1 inhibitor-26 (compound 9a) is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 value of 1.4 μM. HIV-1 inhibitor-26 has low cytotoxicity with a CC50 of 1486 μM in PBMCs. HIV-1 inhibitor-26 can be used for researching AIDS.
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Product Information

Synonyms HIV-1 inhibitor-26|CHEMBL4791559|HY-146308|CS-0498131
Molecular Weight 757.18
Molecular Formula C43H33ClN2O9
Canonical SMILES C1=CC=C(C=C1)C(=O)OCC2C(C(C(O2)N3C=C(C(=O)C4=CC=CC=C43)C(=O)NCC5=CC=C(C=C5)Cl)OC(=O)C6=CC=CC=C6)OC(=O)C7=CC=CC=C7
Purity ≥98% (HPLC)
Solubility 10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 1400
Exact Mass 756.1874583
Target IC50: 1.4 μM (HIV-1 RT)
XLogP3-AA 8.5

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