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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
HCV-IN-40
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| Category | Hepatitis C Virus (HCV) |
| CAS | 2087916-66-1 |
| Description | HCV-IN-40 (Compound 18c) is a potent, orally active hepatitis C virus (HCV) nucleoside inhibitor with EC50 values of 0.259, 0.434 and 0.069 μM against GT1a, GT1b and GT1b CES1 replicons. |
Product Information
| Synonyms | HCV-IN-40|CHEMBL4640294|SCHEMBL18549048|HY-147764|CS-0527363 |
| Molecular Weight | 594.32 |
| Molecular Formula | C21H26BrFN3O9P |
| Canonical SMILES | CCOC(=O)C(C)(C)NP(=O)(OCC1C(C(C(O1)N2C=CC(=O)NC2=O)(F)Br)O)OC3=CC=CC=C3 |
| Purity | ≥98% (HPLC) |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 932 |
| Exact Mass | 593.05741 |
| In Vivo | HCV-IN-40 (Compound 18c) (1 mg/kg) provides very high nucleotide triphosphate (TP) in dog liver. |
| Target | EC50: 0.069 μM (GT1b CES1), 0.259 μM (GT1a), 0.434 μM (GT1b) |
| XLogP3-AA | 1.2 |
