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HCV-IN-37

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Category Hepatitis C Virus (HCV)
CAS 2425804-98-2
Description HCV-IN-37 (Compound 3d) is a potent inhibitor of HCV. HCV-IN-37 is orally available and long-lasting in rat plasma after oral administration to rats by a single dose of 15 mg/kg. The high potency of active derivative HCV-IN-37 is primarily driven by the inhibitory effect on the virus entry stage.
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Product Information

Synonyms HCV-IN-37|HY-144110|CS-0376522
Molecular Weight 515.64
Molecular Formula C31H35F2N5
Canonical SMILES CN1CCCN(CC1)C2=CC(=C(C=C2)C#N)CN3CCN(CC3)C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 742
Exact Mass 515.28605246
Target EC50: 0.005 ± 0.005 μM (HCV)
XLogP3-AA 5

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