GSK8175

Category	Hepatitis C Virus (HCV)
CAS	1423007-82-2
Description	GSK8175 is a non-nucleoside polymerase (NS5B) inhibitor of hepatitis C virus (HCV). GSK8175 is a sulfonamide- benzoxaborole analog with low in vivo clearance across preclinical species and broad-spectrum activity against HCV replicons.

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Synonyms	1423007-82-2\|CHEMBL4467259\|GSK8175\|3-Benzofurancarboxamide, 6-[(7-chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)(methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-\|GSK-2878175\|6-(N-(7-chloro-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide\|6-[(7-chloro-1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)(methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide\|SCHEMBL15251097\|TQP1615\|BDBM50523161\|SB19803\|HY-112047\|CS-0042486\|6-[(7-chloro-1-hydroxy-3H-2,1-benzoxaborol-5-yl)-methylsulfonylamino]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide\|K4P
Molecular Weight	568.81
Molecular Formula	C27H23BClFN2O6S
Canonical SMILES	B1(C2=C(CO1)C=C(C=C2Cl)N(C3=C(C=C4C(=C3)OC(=C4C(=O)NC)C5=CC=C(C=C5)F)C6CC6)S(=O)(=O)C)O
Purity	≥99%
Solubility	Soluble in DMSO
Appearance	Solid powder
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -23 C for long term (months to years).
Complexity	1020
Exact Mass	568.1042437
Target	HCV