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gp120-IN-2

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Category Human immunodeficiency Virus (HIV)
CAS 123629-42-5
Description gp120-IN-2 (compound 4i) is a potent HIV-1 gp120 inhibitor with an IC50 of 7.5 µM and CC50 of 112.93 µM. gp120-IN-2 shows anti-HIV-1 activity. gp120-IN-2 shows cytotoxicity in a dose dependent manner in SUP-T1 cells.
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Product Information

Synonyms 123629-42-5|ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate|gp120-IN-2|ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate|Oprea1_007974|Oprea1_312420|CBDivE_010204|CHEMBL2013078|SCHEMBL15976549|MFCD00128502|STK364150|AKOS000267187|AKOS016037960|NS-05177|HY-144731|CS-0434385|VU0005163-2|SR-01000407730|SR-01000407730-1|F0896-0329|5-Ethoxycarbonyl-4-(4-hydroxy-3-methoxyphenyl)-6-methyl-3,4-dihydropyrimidine-2(1H)-one|5-ethoxycarbonyl-6-methyl-4-(4-hydroxy-3-methoxy-phenyl)-3,4-dihydropyrimidin-2 (1h)-one
Molecular Weight 306.31
Molecular Formula C15H18N2O5
Canonical SMILES CCOC(=O)C1=C(NC(=O)NC1C2=CC(=C(C=C2)O)OC)C
Purity ≥98% (HPLC)
Solubility 10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 477
Exact Mass 306.12157168
Target HIV
XLogP3-AA 1

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