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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
gp120-IN-2
Category | Human immunodeficiency Virus (HIV) |
CAS | 123629-42-5 |
Description | gp120-IN-2 (compound 4i) is a potent HIV-1 gp120 inhibitor with an IC50 of 7.5 µM and CC50 of 112.93 µM. gp120-IN-2 shows anti-HIV-1 activity. gp120-IN-2 shows cytotoxicity in a dose dependent manner in SUP-T1 cells. |
Product Information
Synonyms | 123629-42-5|ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate|gp120-IN-2|ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate|Oprea1_007974|Oprea1_312420|CBDivE_010204|CHEMBL2013078|SCHEMBL15976549|MFCD00128502|STK364150|AKOS000267187|AKOS016037960|NS-05177|HY-144731|CS-0434385|VU0005163-2|SR-01000407730|SR-01000407730-1|F0896-0329|5-Ethoxycarbonyl-4-(4-hydroxy-3-methoxyphenyl)-6-methyl-3,4-dihydropyrimidine-2(1H)-one|5-ethoxycarbonyl-6-methyl-4-(4-hydroxy-3-methoxy-phenyl)-3,4-dihydropyrimidin-2 (1h)-one |
Molecular Weight | 306.31 |
Molecular Formula | C15H18N2O5 |
Canonical SMILES | CCOC(=O)C1=C(NC(=O)NC1C2=CC(=C(C=C2)O)OC)C |
Purity | ≥98% (HPLC) |
Solubility | 10 mM in DMSO |
Appearance | Solid powder |
Storage | Store at -20°C |
Complexity | 477 |
Exact Mass | 306.12157168 |
Target | HIV |
XLogP3-AA | 1 |