-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
gp120-IN-1
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/5948-75-4.gif)
| Category | Human immunodeficiency Virus (HIV) |
| CAS | 5948-75-4 |
| Description | gp120-IN-1 (compound 4e) is a potent HIV-1 gp120 inhibitor with an IC50 of 2.2 µM and CC50 of 100.90 µM. gp120-IN-1 shows anti-HIV-1 activity. gp120-IN-1 shows cytotoxicity in a dose dependent manner in SUP-T1 cells. gp120-IN-1 shows inhibition of gp120-mediated virus enter into cells. |
Product Information
| Synonyms | 5948-75-4|gp120-IN-1|ETHYL 4-(4-HYDROXY-3-METHOXYPHENYL)-6-METHYL-2-SULFANYL-1,4-DIHYDROPYRIMIDINE-5-CARBOXYLATE|ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate|Oprea1_375453|CHEMBL2013079|SCHEMBL13419868|MFCD03804675|STK802514|ZINC00190545|AKOS000653308|AKOS002237797|AKOS002353682|AKOS016045142|AKOS016088640|AKOS016293158|UPCMLD0ENAT5762053:001|ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate|HY-144730|CS-0434381|SR-01000403136|SR-01000488652|SR-01000403136-1|SR-01000488652-1|F0896-0356|ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylate|ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-sulfanyl-1,4-dihydro-5-pyrimidinecarboxylate|ethyl 6-(4-hydroxy-3-methoxyphenyl)-2-mercapto-4-methyl-1,6-dihydro-5-pyrimidinecarboxylate |
| Molecular Weight | 322.38 |
| Molecular Formula | C15H18N2O4S |
| Canonical SMILES | CCOC(=O)C1=C(NC(=S)NC1C2=CC(=C(C=C2)O)OC)C |
| Purity | ≥98% (HPLC) |
| Solubility | 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 480 |
| Exact Mass | 322.09872823 |
| Target | HIV |
| XLogP3-AA | 1.6 |
