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Antiviral API
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Ganoderic-acid-Y
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| Category | Enterovirus (EV) |
| CAS | 86377-52-8 |
| Description | Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating. |
Product Information
| Synonyms | Ganoderic Acid Y|CHEMBL1915760|86377-52-8|Lanosta-7,9(11),24-trien-26-oic acid, 3-hydroxy-, (3beta,24E)-|CHEBI:172035|BDBM50356919|ZINC33831316|HY-125713|CS-0093392|(E,6R)-6-[(3S,5R,10S,13R,14R,17R)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylhept-2-enoic acid |
| Molecular Weight | 454.68 |
| Molecular Formula | C30H46O3 |
| Canonical SMILES | CC(CCC=C(C)C(=O)O)C1CCC2(C1(CC=C3C2=CCC4C3(CCC(C4(C)C)O)C)C)C |
| Purity | 99.07% |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | White to off-white (Solid) |
| Storage | 4°C, protect from light * In solvent : -80°C, 6 months -20°C, 1 month (protect from light) |
| Complexity | 908 |
| Exact Mass | 454.34469533 |
| In Vitro | Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71. |
| PSA | 57.53000 |
| Target | Glucosidase; Enterovirus |
| XLogP3-AA | 7.3 |
