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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
FR 180204
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| Category | Flavivirus |
| CAS | 865362-74-9 |
| Description | FR180204 is a novel and selective inhibitor of extracellular signal-regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis.FR180204 showed activity to inhibit ERKs (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). |
Product Information
| Synonyms | 865362-74-9;FR 180204;FR-180204;ERK inhibitor II;5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE;5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine;4C7X7GV82C;CHEMBL259551;1H-Pyrazolo(3,4-C)pyridazin-3-amine, 5-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-;5-(2-Phenylpyrazolo(1,5-a)pyridin-3-yl)-2H-pyrazolo(3,4-C)pyridazin-3-amine;5-{2-phenylpyrazolo[1,5-a]pyridin-3-yl}-1H-pyrazolo[3,4-c]pyridazin-3-amine;5-{2-phenylpyrazolo[1,5-a]pyridin-3-yl}-2H-pyrazolo[3,4-c]pyridazin-3-amine;UNII-4C7X7GV82C;MLS002607685;MLS006010291;GTPL5966;SCHEMBL1801785;SCHEMBL15017777;CHEBI:91383;HMS3229G06;HMS3414B05;HMS3678B05;HMS3743A05;BCP09857;EX-A1490;BDBM50229978;MFCD14585805;s7524;CCG-206837;DB07794;EE-0007;SB19430;NCGC00183912-01;NCGC00183912-09;NCGC00183912-13;AC-35916;DA-33619;SMR001522560;SMR004701360;F1214;FR 180204?;SW218212-2;FR180204, >=98% (HPLC);BRD-K68756823-001-03-0;BRD-K68756823-001-07-1;Q27077219;ERK Inhibitor II, FR180204 - CAS 865362-74-9;3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-7H-pyrazolo[3,4-c]pyridazin-5-amine;5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3 -ylamine;5-(2-phenylH-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine; |
| IUPAC Name | 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine |
| Molecular Weight | 253.22 |
| Molecular Formula | C9H11N5O4 |
| Canonical SMILES | C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)N=[N+]=[N-] |
| InChI | InChI=1S/C18H13N7/c19-17-12-10-13(20-22-18(12)23-21-17)15-14-8-4-5-9-25(14)24-16(15)11-6-2-1-3-7-11/h1-10H,(H3,19,21,22,23) |
| InChIKey | XVECMUKVOMUNLE-UHFFFAOYSA-N |
| Purity | 0.98 |
| Appearance | Solid powder |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
