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FNC-TP-trisodium

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Category Hepatitis B Virus (HBV)
Description FNC-TP trisodium is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV.
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Product Information

Synonyms FNC-TP (trisodium)|HY-139262A
Molecular Weight 592.11
Molecular Formula C9H11FN6Na3O13P3
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
In Vitro FNC (0.1-10 nM; 24-240 h) is found mainly to accumulate in these HIV-1 target cells, and the retention of FNC-TP is 2-4 times higher than in other types of cells.
In Vivo NC (1-6 mg/kg; a single p.o.) could enter rhesus macaque PBMCs and form the active nucleoside triphosphate FNC-TP.
Target Reverse Transcriptase; HIV; HBV; HCV

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