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Fluticasone-propionate-d5

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Category Enterovirus (EV)
Description Fluticasone propionate-d5 is deuterium labeled Fluticasone (propionate). Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM.
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Product Information

Synonyms Fluticasone propionate-d5|1093258-28-6|[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] 2,2,3,3,3-pentadeuteriopropanoate|80474-14-2|Fluticasone-d5 propionate|HY-B0154S1|AKOS025311244|D74F142|SS-4490|CS-0377496
Molecular Weight 505.6
Molecular Formula C25H31F3O5S
Canonical SMILES CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)SCF
Purity ≥98% (HPLC)
Solubility In vitro:
10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 984
Exact Mass 505.21581347
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs.
PSA 105.97000
Target Glucocorticoid Receptor; Enterovirus; Endogenous Metabolite
XLogP3-AA 4

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