Fluticasone-propionate-d5

Category	Enterovirus (EV)
Description	Fluticasone propionate-d5 is deuterium labeled Fluticasone (propionate). Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM.

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Synonyms	Fluticasone propionate-d5\|1093258-28-6\|[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] 2,2,3,3,3-pentadeuteriopropanoate\|80474-14-2\|Fluticasone-d5 propionate\|HY-B0154S1\|AKOS025311244\|D74F142\|SS-4490\|CS-0377496
Molecular Weight	505.6
Molecular Formula	C25H31F3O5S
Canonical SMILES	CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)SCF
Purity	≥98% (HPLC)
Solubility	In vitro: 10 mM in DMSO
Appearance	Solid powder
Storage	Store at -20°C
Complexity	984
Exact Mass	505.21581347
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs.
PSA	105.97000
Target	Glucocorticoid Receptor; Enterovirus; Endogenous Metabolite
XLogP3-AA	4