-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Fluticasone propionate
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/80474-14-2.gif)
| Category | Enterovirus (EV) |
| CAS | 80474-14-2 |
| Description | Fluticasone propionate (Flonase, Veramyst) is a synthetic corticosteroid which is derived from fluticasone used to treat asthma and allergic rhinitis (hay fever). |
Product Information
| Synonyms | Fluticasone Propionate, Cutivate, Flixonase, Flixotide, Flonase, Flovent; DSSTox_CID_25511; DSSTox_RID_80922; DSSTox_GSID_45511; NCGC00016943-01 |
| IUPAC Name | [(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate |
| Molecular Weight | 500.57 |
| Molecular Formula | C25H31F3O5S |
| Canonical SMILES | CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)SCF |
| InChI | InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16?,18+,19+,22+,23+,24+,25+/m1/s1 |
| InChIKey | WMWTYOKRWGGJOA-ZHLGSTKJSA-N |
| Boiling Point | 568.3±50.0 °C at 760 mmHg |
| Melting Point | 272-273 °C |
| Flash Point | 297.5±30.1 °C |
| Purity | >98% |
| Density | 1.3±0.1 g/cm3 |
| Solubility | Water: 0.51 mg/L |
| Appearance | White Solid |
| Application | the treatment of asthma and allergic rhinitis |
| Storage | Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month |
| Complexity | 984 |
| Exact Mass | 500.18442974 |
| Index Of Refraction | 1.556 |
| In Vitro | Fluticasone propionate inhibits TNFα-induced E-selectin expression, with an IC50 of 1 nM. |
| PSA | 105.97000 |
| Target | Glucocorticoid Receptor; Enterovirus; Endogenous Metabolite |
| Vapor Pressure | 0.0±3.5 mmHg at 25°C |
| XLogP3-AA | 4 |
