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Fluphenazine dihydrochloride

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Category SARS-CoV
CAS 146-56-5
Description Fluphenazine DiHCl is the dihydrochloride salt preparation of Fluphenazine. It has been used to deliver Fluphenazine to biological systems in studies probing the effects and metabolic fates of this commonly used dopamine antagonist.
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Synonyms Fluphenazine dihydrochloride;Fluphenazine hydrochloride;146-56-5;Prolixin;Anatensol;Permitil;Fluphenazine (dihydrochloride);FLUPHENAZINE HCL;Tensofin;Dapotum;Moditen;Squibb 4918;Calmansial;Fluphenazine chloride;OMCA;Flufenazin;Lyorodin;Liogen;Fluorophenazine dihydrochloride;CCRIS 4032;UNII-ZOU145W1XL;EINECS 205-674-1;ZOU145W1XL;NSC 179197;NSC-179197;1-(2-Hydroxyethyl)-4-(3-(2-trifluoromethyl-10-phenothiazinylpropyl)piperazine dihydrochloride;1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-, dihydrochloride;DTXSID00892922;Fluphenazine.2HCl;4-(3-(2-(Trifluoromethyl)phenothiazin-10-yl)propyl)-1-piperazineethanol dihydrochloride;Trancin;A 4077;Fluphenazine hydrochloride [USP:BAN:JAN];Permitil hydrochloride;10-(3-(4-(2-Hydroxyethyl)piperazinyl)propyl)-2-trifluoromethylphenothiazine dihydrochloride;4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazineethanol dihydrochloride;Fluphenazine DiHCl;1-piperazineethanol, 4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-, dihydrochloride;FLUPHENAZINE HYDROCHLORIDE (MART.);FLUPHENAZINE HYDROCHLORIDE [MART.];FLUPHENAZINE HYDROCHLORIDE (USP-RS);Fluphenazine hydrochloride (USP:BAN:JAN);FLUPHENAZINE HYDROCHLORIDE [USP-RS];NSC 62323;NSC179197;FLUPHENAZINE HYDROCHLORIDE (USP IMPURITY);FLUPHENAZINE HYDROCHLORIDE [USP IMPURITY];FLUPHENAZINE HYDROCHLORIDE (USP MONOGRAPH);FLUPHENAZINE HYDROCHLORIDE [USP MONOGRAPH];SR-01000003048;Siqualone;Fluphenazine 2HCl;Prolixin (TN);Prestwick_225;Fluphenazini hydrochloridum;Hydrochloride, Fluphenazine;4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol dihydrochloride;SCHEMBL41634;SPECTRUM1500994;CHEBI:5126;FLUFENAZINE HYDROCHLORIDE;CHEMBL1448187;DTXCID401284964;HMS1568P22;HMS1921O14;BCP18079;HY-A0081;Tox21_500555;MFCD00055212;s4569;Fluphenazine hydrochloride (JAN/USP);AKOS015960787;CCG-212902;CS-4290;LP00555;1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-, dihydrochloride;2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;dihydrochloride;FLUPHENAZINE HYDROCHLORIDE [JAN];FLUPHENAZINE DIHYDROCHLORIDE [MI];NCGC00093941-01;NCGC00093941-02;NCGC00093941-03;NCGC00261240-01;AC-12201;BS-15804;DA-63493;FLUPHENAZINE HYDROCHLORIDE [VANDF];S4569 Fluphenazine (dihydrochloride).cd;FLUPHENAZINE HYDROCHLORIDE [WHO-DD];FLUPHENAZINE HYDROCHLORIDE [WHO-IP];EU-0100555;F1240;NS00079264;C72785;D00791;F 4765;FLUPHENAZINE HYDROCHLORIDE [ORANGE BOOK];FLUPHENAZINI HYDROCHLORIDUM [WHO-IP LATIN];SR-01000003048-2;SR-01000003048-9;W-108125;Fluphenazine.2HCl, 1mg/ml in Methanol (as free base);Q27295826;Z1592690505;Fluphenazine Dihydrochloride 1.0 mg/ml in Methanol (as free base);Fluphenazine dihydrochloride, European Pharmacopoeia (EP) Reference Standard;Fluphenazine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material;Fluphenazine hydrochloride, United States Pharmacopeia (USP) Reference Standard;2-(4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethanol dihydrochloride;2-(4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethanoldihydrochloride;2-(4-{3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl}-1-piperazinyl)ethanol dihydrochloride;2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol,dihydrochloride;
IUPAC Name 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;dihydrochloride
Molecular Weight 510.44
Molecular Formula C22H28Cl2F3N3OS
Canonical SMILES OCCN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(C(F)(F)F)C=C24)CC1.[H]Cl.[H]Cl
InChI InChI=1S/C22H26F3N3OS.2ClH/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29;;/h1-2,4-7,16,29H,3,8-15H2;2*1H
InChIKey MBHNWCYEGXQEIT-UHFFFAOYSA-N
Melting Point 235-237 °C
Purity > 95%
Solubility Soluble to 38mg/mL in DMSO
Appearance White to Off-White Solid
Shelf Life 2 years
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

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