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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Filociclovir
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| Category | Cytomegalovirus (CMV) |
| CAS | 632325-71-4 |
| Description | Filociclovir is a broad-spectrum anti-herpesvirus compound with good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8, with EC50 values ranging from 0.7 μM to 8 μM. |
Product Information
| Synonyms | Cyclopropavir; ZSM-I-62; MBX-400; 2-Amino-9-[(Z)-[2,2-bis(hydroxymethyl)cyclopropylidene]methyl]-3H-purin-6-one; (Z)-2-amino-9-((2,2-bis(hydroxymethyl)cyclopropylidene)methyl)-1,9-dihydro-6H-purin-6-one; (Z)-9-((2,2-bis-(Hydroxymethyl)cyclopropylidene)methyl)guanine; (Z)-2-amino-9-((2,2-bis(hydroxymethyl)cyclopropylidene)methyl)-1H-purin-6(9H)-one |
| IUPAC Name | 2-amino-9-[(Z)-[2,2-bis(hydroxymethyl)cyclopropylidene]methyl]-1H-purin-6-one |
| Molecular Weight | 263.26 |
| Molecular Formula | C11H13N5O3 |
| Canonical SMILES | C1C(=CN2C=NC3=C2NC(=NC3=O)N)C1(CO)CO |
| InChI | InChI=1S/C11H13N5O3/c12-10-14-8-7(9(19)15-10)13-5-16(8)2-6-1-11(6,3-17)4-18/h2,5,17-18H,1,3-4H2,(H3,12,14,15,19)/b6-2- |
| InChIKey | KMUNHOKTIVSFRA-KXFIGUGUSA-N |
| Boiling Point | 628.1±65.0 °C | Condition: Press: 760 Torr |
| Purity | 98% |
| Density | 1.83±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr |
| Solubility | Soluble in DMSO; Insoluble in Water |
| Appearance | Solid powder |
| Application | Filociclovir is antiviral drug candidate and is used for the treatment of cytomegalovirus infection. |
| Storage | Store at -20°C |
| Complexity | 471 |
| Exact Mass | 263.10183929 |
| PSA | 131.04000 |
| Target | CMV; HSV |
| XLogP3-AA | -2.3 |
