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FC131-TFA

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Category Human immunodeficiency Virus (HIV)
Description FC131 TFA is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM.
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Product Information

Synonyms FC131 TFA
Molecular Weight 843.85
Molecular Formula C38H48F3N11O8
Purity 98.38%
Density 1.5±0.1 g/cm3
Solubility In Vitro:
DMSO : 250 mg/mL(296.26 mM;Need ultrasonic)
In Vivo:
1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline
Solubility: ≥ 2.08 mg/mL (2.46 mM); Clear solution
2.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline)
Solubility: ≥ 2.08 mg/mL (2.46 mM); Clear solution
3.Add each solvent one by one:10% DMSO >> 90%corn oil
Solubility: ≥ 2.08 mg/mL (2.46 mM); Clear solution
Appearance White to off-white (Solid)
Storage Sealed storage, away from moisture and light
Powder
-80°C 2 years
-20°C 1 years
* In solvent
-80°C 6 months
-20°C 1 month (sealed storage, away from moisture and light)
Index Of Refraction 1.696
PSA 289.53000
Target CXCR; HIV

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