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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Enviroxime
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| Category | Enterovirus (EV) |
| CAS | 72301-79-2 |
| Description | Enviroxime is a benzimidazole derivative that inhibits the replication of rhinoviruses and poliovirus by targeting protein 3A. Enviroxime exhibits antiviral effects against EV71 with EC50 of 0.15 μM. |
Product Information
| Synonyms | ENVIROXIME;Viroxime;72301-79-2;Viroxime component B;63198-97-0;(NE)-N-[(2-amino-3-propan-2-ylsulfonylbenzimidazol-5-yl)-phenylmethylidene]hydroxylamine;NSC-346230;72301-78-1;LY-122772;(E)-2-Amino-6-benzoyl-1-(isopropylsulfonyl)benzimidazole oxime;LY 122771-72;NSC346230;LY 122772;2-Amino-1-(isopropylsulfonyl)-6-benzimidazole phenyl ketone oxime;1H-Benzimidazol-2-amine, 6-((hydroxyimino)phenylmethyl)-1-((1-methylethyl)sulfonyl)-, (E)-;133013L556;Enviroxima;Enviroximum;Enviroxime [USAN:INN];Enviroximum [INN-Latin];Enviroxima [INN-Spanish];1H-Benzimidazol-2-amine, 6-((E)-(hydroxyimino)phenylmethyl)-1-((1-methylethyl)sulfonyl)-;2-Amino-6-[(E)-alpha-hydroxyiminobenzyl]-1-(isopropylsulfonyl)-1H-benzimidazole;UNII-I5V34WG2BE;NSC 346230;Lilly 122771-72;1H-Benzimidazol-2-amine, 6-[(E)-(hydroxyimino)phenylmethyl]-1-[(1-methylethyl)sulfonyl]-;AR 336;UNII-133013L556;ENVIROXIME [MI];Viroxime [USAN:INN];ENVIROXIME [INN];Enviroxime (USAN/INN);ENVIROXIME [USAN];SCHEMBL3585;(1E)-[2-Amino-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-6-yl]phenylmethanone oxime;I5V34WG2BE;CHEMBL283403;(2-amino-3-isopropylsulfonyl-benzimidazol-5-yl)-phenyl-methanone oxime;DTXSID101024511;(Z,E)-2-Amino-6-benzoyl-1-(isopropylsulfonyl)benzimidazol oxim;EX-A7248;AR-336;AKOS040751693;HY-106312A;6-((Hydroxyimino)phenylmethyl)-1-((1-methylethyl)sulfonyl)-1H-benzimidazol-2-amine;LY122772;DB-223315;CS-0082162;D04012;Q27273110;1H-Benzimidazol-2-amine, 6-((hydroxyimino)phenylmethyl)-1-((1-methylethyl)sulfonyl)-;6-[(E)-(Hydroxyimino)phenylmethyl]-1-[(1-methylethyl)sulfonyl]- 1H-Benzimidazol-2-amine; |
| IUPAC Name | (NE)-N-[(2-amino-3-propan-2-ylsulfonylbenzimidazol-5-yl)-phenylmethylidene]hydroxylamine |
| Molecular Weight | 124.23 |
| Molecular Formula | C3H8OS2 |
| Canonical SMILES | C(C(CS)S)O |
| InChI | InChI=1S/C17H18N4O3S/c1-11(2)25(23,24)21-15-10-13(8-9-14(15)19-17(21)18)16(20-22)12-6-4-3-5-7-12/h3-11,22H,1-2H3,(H2,18,19)/b20-16+ |
| InChIKey | IWKXBHQELWQLHF-CAPFRKAQSA-N |
| Boiling Point | 607.2°C at 760 mmHg |
| Melting Point | 190-192°C |
| Purity | 98% |
| Density | 1.41 g/cm3 |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) |
| Appearance | Solid |
| Application | Coxsackievirus infections; Picornavirus infections |
| Shelf Life | 2 month in rt, long time |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
