Emtricitabine triphosphate tetrasodium salt

Category	Hepatitis B Virus (HBV)
CAS	1188407-46-6
Description	(-)-Emtricitabine triphosphate sodium salt is robustly categorized as an efficacious nucleoside reverse transcriptase inhibitor, illuminating its legalizing role in the therapeutic research against HIV infection. It can seize upon the function of HIV reverse transcriptase to lay siege to the viral replication behavior, thus endeavoring to strike back effectively against this malady.

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Synonyms	1188407-46-6;(-)-EMTRICITABINE TRIPHOSPHATE TETRASODIUM SALT;Sodium ((2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl triphosphate;tetrasodium;[[[(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate;Sodium((2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyltriphosphate;
IUPAC Name	tetrasodium;[[[(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate
Molecular Weight	575.11
Molecular Formula	C8H9FN3Na4O12P3S
Canonical SMILES	O=P(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])OC[C@@H]1O[C@H](N2C=C(F)C(N)=NC2=O)CS1
InChI	InChI=1S/C8H13FN3O12P3S.4Na/c9-4-1-12(8(13)11-7(4)10)5-3-28-6(22-5)2-21-26(17,18)24-27(19,20)23-25(14,15)16;;;;/h1,5-6H,2-3H2,(H,17,18)(H,19,20)(H2,10,11,13)(H2,14,15,16);;;;/q;4*+1/p-4/t5-,6+;;;;/m0..../s1
InChIKey	UVCVKFWKKXBGTF-YPNYOHIOSA-J
Purity	≥ 95% (HPLC)
Appearance	Solid
Application	A metabolite of (-)-Emtricitabine (E525000).