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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
(E)-LHF-535
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| Category | Arenavirus |
| Description | (E)-LHF-535 is the E-isomer of LHF-535. LHF-535 is an antiviral agent, it has EC50s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively. |
Product Information
| Synonyms | (E)-LHF-535|SCHEMBL15201606|HY-112762A|CS-0096146 |
| Molecular Weight | 412.52 |
| Molecular Formula | C27H28N2O2 |
| Canonical SMILES | CC(C)OC1=CC=C(C=C1)N2C=NC3=C2C=CC(=C3)C=CC4=CC=C(C=C4)C(C)(C)O |
| Purity | 99.68% |
| Solubility | In Vitro: DMSO : 60 mg/mL(145.45 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2.5 mg/mL (6.06 mM); Clear solution |
| Appearance | Light yellow to yellow (Solid) |
| Storage | Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month |
| Complexity | 588 |
| Exact Mass | 412.215078140 |
| Target | Arenavirus |
| XLogP3-AA | 5.8 |
