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DL-Pyroglutamic acid
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/149-87-12d.gif)
| Category | Influenza Virus |
| CAS | 149-87-1 |
| Description | Pyroglutamic acid (also known as PCA, 5-oxoproline, pidolic acid, or pyroglutamate for its basic form) is an uncommon and little studied amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam. It is a metabolite in the glutathione cycle that is converted to glutamate by 5-oxoprolinase. Pyroglutamate is found in many proteins including bacteriorhodopsin. N-terminal glutamic acid and glutamine residues can spontaneously cyclize to become pyroglutamate. This is one of several forms of blocked N-terminals which present a problem for N-terminal sequencing using Edman chemistry, which requires a free primary amino group not present in pyroglutamic acid. The enzyme pyroglutamate aminopeptidase can restore a free N-terminus by cleaving off the pyroglutamate residue. |
Product Information
| Synonyms | DL-Pyroglutamic acid;149-87-1;5-Oxopyrrolidine-2-carboxylic acid;2-Pyrrolidone-5-carboxylic acid;5-Oxo-DL-proline;5-OXOPROLINE;DL-Proline, 5-oxo-;DL-2-Pyrrolidone-5-carboxylic acid;DL-Glutamic Acid Lactam;dl-pyrrolidonecarboxylic acid;6VT1YZM21H;CHEBI:16010;D-(+)-Pyroglutamic Acid;MFCD00064322;NSC-40887;OXOPROLINE;DL-Pidolic acid;5-Oxo-L-proline-d5;UNII-6VT1YZM21H;DL-5-Oxoproline;5-Oxoproline #;DL-Pyroglutamicacid;5-OXO-2-PYRROLIDINECARBOXYLIC ACID;EINECS 205-748-3;NSC 40887;D,L-pyroglutamic acid;H-DL-Pyr-OH;(+/-)-pyroglutamic acid;PIDOLIC ACID, DL-;SCHEMBL15791;MLS001304098;PYROGLUTAMIC ACID, DL-;CHEMBL284718;GTPL4703;DTXSID80859174;PROLINE, 5-OXO-, DL-;HMS2269D08;HMS3372F13;1086136-22-2;ALBB-006003;GLP;NSC40887;5-oxo-pyrrolidine-2-carboxylic acid;BBL011576;NSC143034;STK290904;DL-2-Pyrrolidinone-5-carboxylic acid;AKOS000119789;AKOS016338215;CS-W013454;HY-W012738;PB42767;PS-6138;2-Pyrrolidone-5-carboxylic acid, 99%;(+/-)-2-pyrrolidone-5-carboxylic acid;NCGC00263467-03;SMR000112493;SY002490;DB-043022;DB-049588;DL-Pyroglutamic acid; DL-Pyroglutamic acid;AM20080373;G0061;NS00085313;EN300-19515;D77751;AB00443776-07;A808971;SR-01000830710;Q-100175;SR-01000830710-3;Q27887010;5-oxopyrrolidine-2-carboxylic acid;DL-Pyroglutamic acid;F2190-0001;Z104474096;2027729E-091C-4F23-87AA-2D40D8A5C67C;16891-48-8;5-Oxoproline; 5-Oxopyrrolidine-2-carboxylic acid; L-5-Pyrrolidone-2-carboxylic acid; (S)-(-)-2-Pyrrolidone-5-carboxylic acid; |
| IUPAC Name | 5-oxopyrrolidine-2-carboxylic acid |
| Molecular Weight | 129.11 |
| Molecular Formula | C5H7NO3 |
| Canonical SMILES | O=C(C1NC(CC1)=O)O |
| InChI | InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9) |
| InChIKey | ODHCTXKNWHHXJC-UHFFFAOYSA-N |
| Boiling Point | 239.2 °C |
| Melting Point | 183-185 °C (lit.) |
| Purity | ≧ 95% |
| Density | 1.380 g/cm3 |
| Appearance | Solid |
| Storage | Store at 2-8 °C |
