Dendrobine

Category	Influenza Virus
CAS	2115-91-5
Description	Dendrobine, that can be found in the herb of Dendrobium nobile Lindl, produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the blood pressure. Dendrobine on the electrical activity and on amino acid-induced depolarizations of primary afferent terminals were tested on the frog isolated spinal cord.

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Product Information

Synonyms	(3α,6α,7R,8S,9R,10α,11α)-Dendrobane-12-one; Dendroban-12-one; 12-Oxodendrobane; 7,5-(EpoxyMethano)-1H-cyclopent[cd]indol-9-one,decahydro-1,7b-diMethyl-6-(1-Methylethyl)-, (2aS,4aS,5R,6S,7R,7aS,7bR)-; Dendrobine Dendroban-12-one
IUPAC Name	(1S,4S,7S,8R,11R,12R,13S)-2,12-dimethyl-13-propan-2-yl-10-oxa-2-azatetracyclo[5.4.1.18,11.04,12]tridecan-9-one
Molecular Weight	263.38
Molecular Formula	C16H25NO2
Canonical SMILES	CC(C)C1C2C3CCC4C3(C(C1OC2=O)N(C4)C)C
InChI	InChI=1S/C16H25NO2/c1-8(2)11-12-10-6-5-9-7-17(4)14(16(9,10)3)13(11)19-15(12)18/h8-14H,5-7H2,1-4H3/t9-,10+,11+,12-,13-,14-,16+/m1/s1
InChIKey	RYAHJFGVOCZDEI-UFFNCVEVSA-N
Boiling Point	374.6±25.0 °C at 760 mmHg
Melting Point	135-136°C
Flash Point	132.8±14.0 °C
Purity	>98%
Density	1.101 g/cm3
Solubility	In Vitro: DMSO : 33.33 mg/mL(126.55 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (9.49 mM); Clear solution 2.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (9.49 mM); Clear solution 3.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2.5 mg/mL (9.49 mM); Clear solution
Appearance	Cryst.
Application	Analgesic/antipyretic
Storage	4°C, protect from light * In solvent : -80°C, 6 months -20°C, 1 month (protect from light)
Complexity	435
Exact Mass	263.188529040
Index Of Refraction	1.526
PSA	29.54000
Target	Influenza virus \| MMP(e.g.TIMP) \| Bcl-2/Bax \| Caspase
Vapor Pressure	0.0±0.8 mmHg at 25°C
XLogP3-AA	3