-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
DDX3-IN-1
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| Category | Hepatitis C Virus (HCV) |
| CAS | 1919828-83-3 |
| Description | DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor for HCV and HIV, respectively. |
Product Information
| Synonyms | DDX3-IN-1|1919828-83-3|CHEMBL4164410|SCHEMBL17978530|HY-121832|CS-0083520|1-[4-(4-methyltriazol-1-yl)phenyl]-3-(o-tolyl)urea|1-(2-methylphenyl)-3-[4-(4-methyltriazol-1-yl)phenyl]urea |
| Molecular Weight | 307.35 |
| Molecular Formula | C17H17N5O |
| Canonical SMILES | CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)N3C=C(N=N3)C |
| Purity | 99.57% |
| Solubility | In Vitro: DMSO : 125 mg/mL(406.70 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2.08 mg/mL (6.77 mM); Clear solution 2.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.08 mg/mL (6.77 mM); Clear solution 3.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2.08 mg/mL (6.77 mM); Clear solution |
| Appearance | Light Yellow to Yellow Solid |
| Storage | Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month |
| Complexity | 396 |
| Exact Mass | 307.14331018 |
| Target | HIV; HCV |
| XLogP3-AA | 2.7 |
