ddCTP

Category	Human immunodeficiency Virus (HIV)
CAS	66004-77-1
Description	ddCTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddCTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dCTP in cells.

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Synonyms	2',3'-Dideoxycytidine-5'-Triphosphate; Zalcitabine triphosphate; Cytidine 5'-(tetrahydrogen triphosphate), 2',3'-dideoxy-
IUPAC Name	[[(2S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Molecular Weight	451.16 (free acid)
Molecular Formula	C9H16N3O12P3 (free acid)
Canonical SMILES	C1CC(OC1COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N2C=CC(=NC2=O)N
InChI	InChI=1S/C9H16N3O12P3/c10-7-3-4-12(9(13)11-7)8-2-1-6(22-8)5-21-26(17,18)24-27(19,20)23-25(14,15)16/h3-4,6,8H,1-2,5H2,(H,17,18)(H,19,20)(H2,10,11,13)(H2,14,15,16)/t6-,8+/m0/s1
InChIKey	ARLKCWCREKRROD-POYBYMJQSA-N
Boiling Point	744.1±70.0 °C at 760 mmHg
Flash Point	403.8°C
Purity	≥95% by AX-HPLC
Density	2.3±0.1 g/cm3
Solubility	water: 1 mg/mL, clear, colorless
Appearance	clear aqueous solution
Application	ddCTP is an inhibitor of reverse transcriptases from retroviruses.
Storage	store at -20 °C
Complexity	792
Exact Mass	450.99468395
Index Of Refraction	1.75
PSA	260.38000
Target	DNA/RNA Synthesis; HIV Protease
XLogP3-AA	-5.5