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Cys-TAT (47-57)

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Category Human immunodeficiency Virus (HIV)
CAS 583836-55-9
Description It is an arginine-rich cell-penetrating peptide derived from HIV-1 transactivator protein.
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Product Information

Synonyms Cys-[HIV-Tat (47-57)]; (Cys46)-HIV-1 Tat Protein (46-57) Amide; H-Cys-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2; L-cysteinyl-L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-argininamide
IUPAC Name (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
Molecular Weight 1661.99
Molecular Formula C67H124N34O14S
Canonical SMILES C1=CC(=CC=C1CC(C(=O)NCC(=O)NC(CCCN=C(N)N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)N)NC(=O)C(CS)N)O
InChI InChI=1S/C67H124N34O14S/c68-25-3-1-11-41(94-54(108)40(14-6-28-86-63(75)76)92-50(104)34-91-53(107)48(101-52(106)38(70)35-116)33-36-19-21-37(102)22-20-36)56(110)95-42(12-2-4-26-69)57(111)97-44(16-8-30-88-65(79)80)58(112)98-46(18-10-32-90-67(83)84)60(114)100-47(23-24-49(71)103)61(115)99-45(17-9-31-89-66(81)82)59(113)96-43(15-7-29-87-64(77)78)55(109)93-39(51(72)105)13-5-27-85-62(73)74/h19-22,38-48,102,116H,1-18,23-35,68-70H2,(H2,71,103)(H2,72,105)(H,91,107)(H,92,104)(H,93,109)(H,94,108)(H,95,110)(H,96,113)(H,97,111)(H,98,112)(H,99,115)(H,100,114)(H,101,106)(H4,73,74,85)(H4,75,76,86)(H4,77,78,87)(H4,79,80,88)(H4,81,82,89)(H4,83,84,90)/t38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-/m0/s1
InChIKey RUHMHCCLOQWKOB-AIFXSXIMSA-N
Boiling Point 1604.2±75.0°C at 760 mmHg
Purity ≥95%
Density 1.6±0.1 g/cm3
Solubility Soluble in Water
Appearance Solid powder
Storage Store at -20°C
Target HIV

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