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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Cyclophilin inhibitor 1
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| Category | Hepatitis C Virus (HCV) |
| CAS | 1509904-96-4 |
| Description | Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin inhibitor, and it shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a. |
Product Information
| Synonyms | Cyclophilin inhibitor 1|CHEMBL4176386|SCHEMBL15907884|BDBM50450030|HY-112712|CS-0062849 |
| Molecular Weight | 593.67 |
| Molecular Formula | C31H39N5O7 |
| Canonical SMILES | CC1C2=NC3=C(C=CC(=C3)C=CC4(COCOC4)C(=O)OC(C(=O)NC(C(=O)N5CCCC(N5)C(=O)N1)C)C(C)C)C=C2 |
| InChI | InChI=1S/C31H39N5O7/c1-18(2)26-28(38)33-20(4)29(39)36-13-5-6-24(35-36)27(37)32-19(3)23-10-9-22-8-7-21(14-25(22)34-23)11-12-31(30(40)43-26)15-41-17-42-16-31/h7-12,14,18-20,24,26,35H,5-6,13,15-17H2,1-4H3,(H,32,37)(H,33,38)/b12-11+/t19-,20+,24+,26+/m1/s1 |
| InChIKey | IVDFPOWAIHEKAG-GOZMEEBJSA-N |
| Purity | >98.00% |
| Solubility | DMSO: 70 mg/mL |
| Appearance | Solid powder |
| Storage | -20°C Refrigerated long-term storage |
| Complexity | 1080 |
| Exact Mass | 593.28494860 |
| In Vitro | Cyclophilin inhibitor 1 (Compound 3) inhibits HCV 2a activity, with an EC50 of 98 nM. |
| Target | Kd: 5 nM (Cyclophilin A) EC50: 98 nM (HCV 2a) |
| XLogP3-AA | 2.5 |