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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Cyclic-HPMPC
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| Category | Cytomegalovirus (CMV) |
| CAS | 127757-45-3 |
| Description | Cyclic HPMPC is a potent antiviral agent. Cyclic HPMPC can increase arterial oxygen saturation levels in lethal vaccinia virus (IHD strain)-infected mice. Cyclic HPMPC improves the outcome of congenital guinea pig cytomegalovirus (GPCMV) infection and decreases viral replication in guinea pig model. |
Product Information
| Synonyms | Chpmpc|cCDV|Cyclic-hpmpc|Cyclic HPMPC|CYCLIC CIDOFOVIR|Cyclic(S)-HPMPC|127757-45-3|UNII-BO8PRP86RH|BO8PRP86RH|Cyclic-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine|GS 930|1-((2-Hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl)cytosine|(S)-4-Amino-1-((2-hydroxy-1,4,2-dioxaphosphorinan-5-yl)methyl)-2(1H)-pyrimidinone P-oxide|cyclic HPMPC, GS 0930|SCHEMBL140858|CHEMBL392630|DTXSID00155660|BDBM50485549|2(1H)-Pyrimidinone, 4-amino-1-((2-hydroxy-1,4,2-dioxaphosphorinan-5-yl)methyl)-, P-oxide, (S)-|HY-147014|1-[((5)-2-Hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine|1-[((s)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine|1-[[(S)-2-Hydroxy-2-oxo-1,4,2-dioxaphosphorinane-5-yl]methyl]cytosine|1-(((S)-2-Hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl)cytosine (cyclic HPMPC)|(5S)-5-[(4-Amino-1,2-dihydro-2-oxopyrimidine-1-yl)methyl]-2-hydroxy-1,4,2-dioxaphosphorinane 2-oxide|4-amino-1-[[(5S)-2-hydroxy-2-oxo-1,4,2$l^{5}-dioxaphosphinan-5-yl]methyl]pyrimidin-2-one|4-amino-1-[[(5S)-2-hydroxy-2-oxo-1,4,2lambda5-dioxaphosphinan-5-yl]methyl]pyrimidin-2-one |
| Molecular Weight | 261.17 |
| Molecular Formula | C8H12N3O5P |
| Canonical SMILES | C1C(OCP(=O)(O1)O)CN2C=CC(=NC2=O)N |
| Boiling Point | 495.6ºC at 760mmHg |
| Flash Point | 253.5ºC |
| Purity | ≥98% (HPLC) |
| Density | 1.83g/cm3 |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 435 |
| Exact Mass | 261.05145749 |
| Index Of Refraction | 1.709 |
| PSA | 127.47000 |
| Target | CMV; Orthopoxvirus |
| Vapor Pressure | 3.57E-11mmHg at 25°C |
| XLogP3-AA | -2.6 |
