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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Corydine
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 2505-56-8 |
| Description | Corydine is a naturally occurring alkaloid which can be extracted from plants such as Croton echinocarpus leaves. Corydin is efficient on inhibiting reverse transcriptase (RT) activity with an IC50 of 356.8 μg/mL. Corydine displays significant in vitro anti-HIV potential, inhibiting 40% of the HIV-1 reverse transcriptase enzyme activity at a concentration of 450 μg/mL of Corydine. |
Product Information
| Synonyms | Corydine|476-69-7|(+)-Corydine|UNII-1O1D15OP5R|Glaucentrin|Glaucentrine|d-Corydine|(S)-(+)-Corydine|1O1D15OP5R|CHEMBL489524|(6aS)-2,10,11-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol|O(sup 11)-Methylcorytuberine|4H-Dibenzo(de,g)quinolin-1-ol, 5,6,6a,7-tetrahydro-2,10,11-trimethoxy-6-methyl-, (S)-|BRN 0095568|(S)-Corydine|5-21-06-00134 (Beilstein Handbook Reference)|SCHEMBL680230|6a-alpha-APORPHIN-1-OL, 2,10,11-TRIMETHOXY-|DTXSID00963883|2,10,11-Trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol|HY-N2571|ZINC1651264|BDBM50250271|MFCD00076020|AKOS000277266|AC-35116|CS-0022908|Q27252668|UNII-24S71U195F component IDQUPXZJURZAGF-ZDUSSCGKSA-N|(S)-2,10,11-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol |
| Molecular Weight | 341.401 |
| Molecular Formula | C20H23NO4 |
| Canonical SMILES | CN1CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)OC)O)OC |
| Purity | >95.00% |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 475 |
| Exact Mass | 341.16270821 |
| PSA | 51.16000 |
| Target | Reverse Transcriptase; HIV |
| XLogP3-AA | 2.6 |
