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Chloroquine-d4-phosphate

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Category Human immunodeficiency Virus (HIV)
Description Chloroquine-d4 phosphate is the deuterium labeled Chloroquine phosphate. Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an Autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM).
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Product Information

Synonyms Chloroquine-d4 (phosphate)|CS-0370956
Molecular Weight 519.89
Molecular Formula C18H32ClN3O8P2
Purity ≥98% (HPLC)
Solubility DMSO (Sparingly), Methanol (Slightly), Water (Slightly, Sonicated)
Appearance Light Yellow to Yellow Solid
Storage Store at -20°C
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs.
Target Parasite; Autophagy; SARS-CoV; Toll-like Receptor (TLR); HIV; Antibiotic

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