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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Chloroquine-d4-phosphate
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| Category | Human immunodeficiency Virus (HIV) |
| Description | Chloroquine-d4 phosphate is the deuterium labeled Chloroquine phosphate. Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an Autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM). |
Product Information
| Synonyms | Chloroquine-d4 (phosphate)|CS-0370956 |
| Molecular Weight | 519.89 |
| Molecular Formula | C18H32ClN3O8P2 |
| Purity | ≥98% (HPLC) |
| Solubility | DMSO (Sparingly), Methanol (Slightly), Water (Slightly, Sonicated) |
| Appearance | Light Yellow to Yellow Solid |
| Storage | Store at -20°C |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs. |
| Target | Parasite; Autophagy; SARS-CoV; Toll-like Receptor (TLR); HIV; Antibiotic |
