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Chlorogenic acid

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Category HIF/HIF Prolyl-Hydroxylase
CAS 327-97-9
Description Chlorogenic acid is a hydroxycinnamic acid and a member of a family of naturally occurring organic compounds. Chlorogenic acid exhibits an anti-inflammatory effect, and reduce blood pressure. Chlorogenic acid has a wide range of biological activities. Modern scientific research on the biological activity of chlorogenic acid has penetrated into many fields such as food, health care, medicine and daily chemical industry.
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Product Information

Synonyms NSC 407296, Heriguard
Molecular Weight 354.31
Molecular Formula C16H18O9
Canonical SMILES C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O
InChI InChI=1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(20)25-12-7-16(24,15(22)23)6-11(19)14(12)21/h1-5,11-12,14,17-19,21,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14-,16+/m1/s1
InChIKey CWVRJTMFETXNAD-JUHZACGLSA-N
Boiling Point 665.0±55.0 °C at 760 mmHg
Melting Point 205-209°C
Flash Point 245.5°C
Purity >98%
Density 1.7±0.1 g/cm3
Solubility In Vitro:
DMSO : 100 mg/mL(282.24 mM;Need ultrasonic)
In Vivo:
1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline
Solubility: ≥ 2.5 mg/mL (7.06 mM); Clear solution
2.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline)
Solubility: ≥ 2.5 mg/mL (7.06 mM); Clear solution
3.Add each solvent one by one:10% DMSO >> 90%corn oil
Solubility: ≥ 2.5 mg/mL (7.06 mM); Clear solution
Appearance Powder
Application Ingredient of health care products.
Storage 0-6°C
Assay 0.98
Complexity 534
Exact Mass 354.09508215
PSA 164.75000
Target HIF/HIF Prolyl-Hydroxylase; Reactive Oxygen Species; Bacterial; Influenza Virus;
XLogP3-AA -0.4

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