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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Bvdv-IN-1
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| Category | Flavivirus |
| CAS | 345651-04-9 |
| Description | BVDV-IN-1, a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV) (EC50 = 1.8 μM), has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC). It directly binds to a hydrophobic pocket of the BVDV RNA-dependent RNA polymerase (RdRp), and inhibits the replication of TSC-resistant BVDV variants in vitro. |
Product Information
| Synonyms | BVDV-IN-1;345651-04-9;2-[4-(2-phenylquinazolin-4-yl)piperazin-1-yl]ethanol;2-(4-(2-Phenylquinazolin-4-yl)piperazin-1-yl)ethanol;EX-A5593;AKOS000915262;MS-25053;HY-131976;CS-0145660;G13690; |
| IUPAC Name | 2-[4-(2-phenylquinazolin-4-yl)piperazin-1-yl]ethanol |
| Molecular Weight | 334.41 |
| Molecular Formula | C20H22N4O |
| Canonical SMILES | OCCN1CCN(C2=C3C=CC=CC3=NC(C4=CC=CC=C4)=N2)CC1 |
| InChI | InChI=1S/C20H22N4O/c25-15-14-23-10-12-24(13-11-23)20-17-8-4-5-9-18(17)21-19(22-20)16-6-2-1-3-7-16/h1-9,25H,10-15H2 |
| InChIKey | DPFKMYSBAMEGQK-UHFFFAOYSA-N |
| Boiling Point | 431.6±45.0°C at 760 mmHg |
| Purity | ≥98% |
| Density | 1.2±0.1 g/cm3 |
| Solubility | Soluble in DMSO |
| Appearance | Solid |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
