-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Bifendate
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/73536-69-3.gif)
| Category | Human immunodeficiency Virus (HIV) |
| CAS | 73536-69-3 |
| Description | Bifendate is a synthetic intermediate of schisandrin C, a dibenzocyclooctadiene derivative derived from lignans used in traditional medicine and also a anti-HBV drug used in the treatment of chronic hepatitis B. It has been used in some countries as a hepatoprotectant adjuvant in the treatment of liver diseases, such as chronic viral hepatitis or drug-induced hepatic damage. |
Product Information
| Synonyms | 7,7'-Dimethoxy-[4,4'-Bi-1,3-benzodioxole]-5,5'-dicarboxylic Acid 5,5'-Dimethyl Ester; DDB; Dimethyl 4,4'-Dimethoxy-5,6,5',6'-di(methylenedioxy)biphenyl-2,2'-dicarboxylate; Dimethyl dicarboxylate Biphenyl; α-DDB |
| IUPAC Name | methyl 7-methoxy-4-(7-methoxy-5-methoxycarbonyl-1,3-benzodioxol-4-yl)-1,3-benzodioxole-5-carboxylate |
| Molecular Weight | 418.36 |
| Molecular Formula | C20H18O10 |
| Canonical SMILES | COC1=C2C(=C(C(=C1)C(=O)OC)C3=C4C(=C(C=C3C(=O)OC)OC)OCO4)OCO2 |
| InChI | InChI=1S/C20H18O10/c1-23-11-5-9(19(21)25-3)13(17-15(11)27-7-29-17)14-10(20(22)26-4)6-12(24-2)16-18(14)30-8-28-16/h5-6H,7-8H2,1-4H3 |
| InChIKey | JMZOMFYRADAWOG-UHFFFAOYSA-N |
| Boiling Point | 606.9±55.0 °C at 760 mmHg |
| Melting Point | 179-181°C |
| Flash Point | 265.9±31.5 °C |
| Purity | 97.0%~103.0% |
| Density | 1.4±0.1 g/cm3 |
| Solubility | In Vitro: DMSO : 50 mg/mL(119.52 mM;Need ultrasonic) H2O : 1 mg/mL(2.39 mM;ultrasonic and warming and heat to 80°C) In Vivo: 1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution 2.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution |
| Appearance | White crystalline powder |
| Application | Cytochrome P-450 Enzyme Inhibitors |
| Storage | 4°C, protect from light, stored under nitrogen * In solvent : -80°C 6 months; -20°C 1 month (protect from light, stored under nitrogen) |
| Complexity | 587 |
| Exact Mass | 418.08999677 |
| Index Of Refraction | 1.580 |
| PSA | 107.98000 |
| Target | HBV |
| Vapor Pressure | 0.0±1.7 mmHg at 25°C |
| XLogP3-AA | 2.8 |
