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Antiviral API
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BC-11 hydrobromide
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| Category | SARS-CoV |
| CAS | 443776-49-6 |
| Description | BC 11 hydrobromide is a selective urokinase (uPA) inhibitor (IC50 = 8.2 μM) with no activity at 8 other related enzymes. BC 11 inhibits clot lysis displaying no effect on clot formation. It also decreases viability of MDA-MB231 breast cancer cells in vitro. |
Product Information
| Synonyms | BC 11 hydrobromide;443776-49-6;BC-11 hydrobromide;BC11 hydrobromide;(4-((Carbamimidoylthio)methyl)phenyl)boronic acid hydrobromide;BC-11 (hydrobromide);uPA inhibitor BC-11 hydrobromide;GLXC-15931;AKOS024458122;DA-61527;HY-108447;CS-0028707;G82409;4-(Carbamimidoylthiomethyl)phenylboronic acid hydrobromide;[4-(carbamimidoylsulfanylmethyl)phenyl]boronic acid;hydrobromide;{4-[(Carbamimidoylsulfanyl)methyl]phenyl}boronic acid hydrobromide; |
| IUPAC Name | [4-(carbamimidoylsulfanylmethyl)phenyl]boronic acid;hydrobromide |
| Molecular Weight | 290.97 |
| Molecular Formula | C8H12BBrN2O2S |
| Canonical SMILES | NC(SCC1=CC=C(B(O)O)C=C1)=N.[H]Br |
| InChI | InChI=1S/C8H11BN2O2S.BrH/c10-8(11)14-5-6-1-3-7(4-2-6)9(12)13;/h1-4,12-13H,5H2,(H3,10,11);1H |
| InChIKey | PAFZAMOVHIRQOD-UHFFFAOYSA-N |
| Appearance | Solid |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
