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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
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- Rabies virus (RABV)
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- SARS-CoV
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- Virus Protease
- West Nile virus
- Antiviral intermediates
BA-53038B
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| Category | Hepatitis B Virus (HBV) |
| CAS | 2306195-65-1 |
| Description | BA-53038B is a HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner, with an EC50 value of 3.32 μM. |
Product Information
| Synonyms | BA-53038B|2306195-65-1|HY-114314|CS-0082064|N-(3-Chlorophenyl)bicyclo[4.1.0]heptane-7-carboxamide |
| IUPAC Name | N-(3-chlorophenyl)bicyclo[4.1.0]heptane-7-carboxamide |
| Molecular Weight | 249.74 |
| Molecular Formula | C14H16ClNO |
| Canonical SMILES | O=C(NC1=CC=CC(Cl)=C1)C2C3CCCCC32 |
| InChI | InChI=1S/C14H16ClNO/c15-9-4-3-5-10(8-9)16-14(17)13-11-6-1-2-7-12(11)13/h3-5,8,11-13H,1-2,6-7H2,(H,16,17) |
| InChIKey | ZLCICHYECNOTGG-UHFFFAOYSA-N |
| Purity | 98.10% |
| Solubility | Soluble in DMSO. |
| Appearance | Solid |
| Storage | Powder: -20°C 3 years 4°C 2 years In solvent: -80°C 6 months -20°C 1 months |
| Complexity | 295 |
| Exact Mass | 249.0920418 |
| In Vitro | BA-53038B reduced the amount of hypophosphorylated core protein and promoted the assembly of empty capsids with slow electrophoresis mobility. |
| Target | EC50: 3.32 μM (HBV nucleocapsid assembly) |
| XLogP3-AA | 3.9 |
