AZD-7295

Category	HCV Protease
CAS	929890-64-2
Description	AZD-7295 is a HCV NS5A protein inhibitor, with an EC50 of 7 nM for GT-1b replicon.

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Synonyms	AZD-7295\|929890-64-2\|AZD7295\|UNII-102MC1467J\|AZD 7295\|102MC1467J\|4-[5-(cyclopropanecarbonylamino)-2-(trifluoromethoxy)phenyl]-N-[4-[(4-propylsulfonylpiperazin-1-yl)methyl]phenyl]benzamide\|5'-[(Cyclopropylcarbonyl)amino]-N-[4-[[4-(propylsulfonyl)-1-piperazinyl]methyl]phenyl]-2'-(trifluoromethoxy)[1,1'-biphenyl]-4-carboxamide\|A-689\|A-831\|SCHEMBL1505141\|CHEMBL4297353\|DB12724\|HY-111087\|CS-0034191\|Q27251097\|5'-(Cyclopropanecarbonyl-amino)-2'-trifluoromethoxy-biphenyl-4-carboxylic acid {4-[4-(propane-1-sulfonyl)-piperazin-1-ylmethyl]-phenyl}-amide\|5'-[(Cyclopropylcarbonyl)amino]-N-(4-{[4-(propylsulfonyl)piperazin-1-yl]methyl}phenyl)-2'-(trifluoromethoxy)biphenyl-4-carboxamide
Molecular Weight	644.7
Molecular Formula	C32H35F3N4O5S
Canonical SMILES	CCCS(=O)(=O)N1CCN(CC1)CC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)C4=C(C=CC(=C4)NC(=O)C5CC5)OC(F)(F)F
Purity	>98.00%
Solubility	Soluble in DMSO, not in water
Appearance	Solid powder
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Complexity	1090
Exact Mass	644.22802589
Target	HCV Protease
XLogP3-AA	5