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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
AZD-7295
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| Category | HCV Protease |
| CAS | 929890-64-2 |
| Description | AZD-7295 is a HCV NS5A protein inhibitor, with an EC50 of 7 nM for GT-1b replicon. |
Product Information
| Synonyms | AZD-7295|929890-64-2|AZD7295|UNII-102MC1467J|AZD 7295|102MC1467J|4-[5-(cyclopropanecarbonylamino)-2-(trifluoromethoxy)phenyl]-N-[4-[(4-propylsulfonylpiperazin-1-yl)methyl]phenyl]benzamide|5'-[(Cyclopropylcarbonyl)amino]-N-[4-[[4-(propylsulfonyl)-1-piperazinyl]methyl]phenyl]-2'-(trifluoromethoxy)[1,1'-biphenyl]-4-carboxamide|A-689|A-831|SCHEMBL1505141|CHEMBL4297353|DB12724|HY-111087|CS-0034191|Q27251097|5'-(Cyclopropanecarbonyl-amino)-2'-trifluoromethoxy-biphenyl-4-carboxylic acid {4-[4-(propane-1-sulfonyl)-piperazin-1-ylmethyl]-phenyl}-amide|5'-[(Cyclopropylcarbonyl)amino]-N-(4-{[4-(propylsulfonyl)piperazin-1-yl]methyl}phenyl)-2'-(trifluoromethoxy)biphenyl-4-carboxamide |
| Molecular Weight | 644.7 |
| Molecular Formula | C32H35F3N4O5S |
| Canonical SMILES | CCCS(=O)(=O)N1CCN(CC1)CC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)C4=C(C=CC(=C4)NC(=O)C5CC5)OC(F)(F)F |
| Purity | >98.00% |
| Solubility | Soluble in DMSO, not in water |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Complexity | 1090 |
| Exact Mass | 644.22802589 |
| Target | HCV Protease |
| XLogP3-AA | 5 |
