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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Nipah virus
- Orthopoxvirus
- Others
- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Tobacco mosaic virus (TMV)
- Vesicular stomatitis virus (VSV)
- Virus Protease
- West Nile virus
- Antiviral intermediates
Artemisinin-d4
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| Category | Hepatitis C Virus (HCV) |
| Description | Artemisinin-d4 (Qinghaosu-d4) is the deuterium labeled Artemisinin. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial drug isolated from the aerial parts of Artemisia annua L. plants. It inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects. |
Product Information
| Synonyms | Artemisinin-d4|HY-B0094S1|CS-0373117 |
| Molecular Weight | 286.36 |
| Molecular Formula | C15H22O5 |
| Canonical SMILES | CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C |
| Boiling Point | 585.4±50.0 °C at 760 mmHg |
| Flash Point | 221.8±30.0 °C |
| Purity | ≥98% (HPLC) |
| Density | 1.3±0.1 g/cm3 |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 452 |
| Exact Mass | 550.314209 |
| Index Of Refraction | 1.562 |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and Metabolic profiles of drugs. |
| Target | HCV; Parasite; Akt; Ferroptosis |
| Vapor Pressure | 0.0±1.6 mmHg at 25°C |
| XLogP3-AA | 2.8 |