ara-Adenosine-5'-monophosphate (ara-AMP)

Category	Hepatitis B Virus (HBV)
CAS	29984-33-6
Description	ara-Adenosine-5'-monophosphate (ara-AMP) is an adenosine monophosphate analog with antiviral and possibly antineoplastic properties. It inhibits DNA polymerase and also acts as a chain terminator in DNA replication.

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Synonyms	Vidarabine monophosphate, Sodium salt
IUPAC Name	[(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
Molecular Weight	347.22 (free acid)
Molecular Formula	C10H14N5O7P (free acid)
Canonical SMILES	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O
InChI	InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7+,10-/m1/s1
InChIKey	UDMBCSSLTHHNCD-UHTZMRCNSA-N
Boiling Point	798.5±70.0 °C at 760 mmHg
Melting Point	213°C
Flash Point	436.7±35.7 °C
Purity	≥ 95% by HPLC
Density	2.3±0.1 g/cm3
Solubility	In vitro: 10 mM in DMSO
Appearance	white powder
Storage	Store at -20°C
Complexity	481
Exact Mass	347.06308480
Index Of Refraction	1.905
PSA	195.88000
Target	HBV; Antibiotic
Vapor Pressure	0.0±3.0 mmHg at 25°C
XLogP3-AA	-3.5