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Anti-Influenza-agent-3

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Category Influenza Virus
Description Anti-Influenza agent 3 is a potent anti-influenza agent with EC50 values of 3.29, 2.45 µM for A/HK/68 (H3N2, M2-WT), A/WSN/33 (H1N1, M2-S31N) strain, respectively. Anti-Influenza agent 3 shows low cytotoxicity for MDCK epithelial
cells. Anti-Influenza agent 3 inhibits the M2 WT and S31N ion channel conductivity.
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Product Information

Synonyms Anti-Influenza agent 3|HY-147881|CS-0529831
Molecular Weight 311.87
Molecular Formula C16H22ClNOS
Canonical SMILES CC1C(CC2CC1C2(C)C)C(=NO)C3=CC(=C(S3)Cl)C
Purity ≥98% (HPLC)
Solubility 10 mM in DMSO
Appearance Solid powder
Storage Store at -20°C
Complexity 425
Exact Mass 311.1110632
In Vitro Anti-Influenza agent 3 shows lowe cytotoxicity for MDCK epithelial cells with an TC50 of >173.14 µM.
Anti-Influenza agent 3 (100 µM) inhibits the M2 WT and S31N ion channel conductivity in 293 T-Rex cells.
In Vivo Anti-Influenza agent 3 shows lowe cytotoxicity for MDCK epithelial cells with an TC50 of >173.14 µm.
Target Influenza Virus
XLogP3-AA 6.1

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