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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
Anti-Influenza-agent-3
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| Category | Influenza Virus |
| Description | Anti-Influenza agent 3 is a potent anti-influenza agent with EC50 values of 3.29, 2.45 µM for A/HK/68 (H3N2, M2-WT), A/WSN/33 (H1N1, M2-S31N) strain, respectively. Anti-Influenza agent 3 shows low cytotoxicity for MDCK epithelial cells. Anti-Influenza agent 3 inhibits the M2 WT and S31N ion channel conductivity. |
Product Information
| Synonyms | Anti-Influenza agent 3|HY-147881|CS-0529831 |
| Molecular Weight | 311.87 |
| Molecular Formula | C16H22ClNOS |
| Canonical SMILES | CC1C(CC2CC1C2(C)C)C(=NO)C3=CC(=C(S3)Cl)C |
| Purity | ≥98% (HPLC) |
| Solubility | 10 mM in DMSO |
| Appearance | Solid powder |
| Storage | Store at -20°C |
| Complexity | 425 |
| Exact Mass | 311.1110632 |
| In Vitro | Anti-Influenza agent 3 shows lowe cytotoxicity for MDCK epithelial cells with an TC50 of >173.14 µM. Anti-Influenza agent 3 (100 µM) inhibits the M2 WT and S31N ion channel conductivity in 293 T-Rex cells. |
| In Vivo | Anti-Influenza agent 3 shows lowe cytotoxicity for MDCK epithelial cells with an TC50 of >173.14 µm. |
| Target | Influenza Virus |
| XLogP3-AA | 6.1 |
