-
Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Dengue virus
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- Flavivirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
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- Influenza Virus
- Nipah virus
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- Rabies virus (RABV)
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
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- Virus Protease
- West Nile virus
- Antiviral intermediates
Anguizole
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| Category | Hepatitis C Virus (HCV) |
| CAS | 442666-98-0 |
| Description | Anguizole is a small molecule inhibitor of HCV replication and alters NS4B's subcellular distribution. |
Product Information
| Synonyms | Anguizole|442666-98-0|7-[chloro(difluoro)methyl]-5-(furan-2-yl)-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide|CS-0558|CHEMBL2170006|SCHEMBL14366829|DTXSID30359937|ZINC720413|BCP21132|Anguizole,CAS:442666-98-0|AKOS025149511|NCGC00379046-01|HY-13321|A924203|7-(Chlorodifluoromethyl)-5-(2-furanyl)-N-(2-thienylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide|7-[chloro(difluoro)methyl]-5-(2-furyl)-N-(2-thienylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide|7-[chloro(difluoro)methyl]-5-furan-2-yl-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidine-2 carboxamide |
| IUPAC Name | 7-[chloro(difluoro)methyl]-5-(furan-2-yl)-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide |
| Molecular Weight | 408.81 |
| Molecular Formula | C17H11ClF2N4O2S |
| Canonical SMILES | C1=COC(=C1)C2=NC3=CC(=NN3C(=C2)C(F)(F)Cl)C(=O)NCC4=CC=CS4 |
| InChI | InChI=1S/C17H11ClF2N4O2S/c18-17(19,20)14-7-11(13-4-1-5-26-13)22-15-8-12(23-24(14)15)16(25)21-9-10-3-2-6-27-10/h1-8H,9H2,(H,21,25) |
| InChIKey | GBNREAYNZPJROB-UHFFFAOYSA-N |
| Purity | >98% |
| Solubility | In Vitro: DMSO : 50 mg/mL(122.31 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2.5 mg/mL (6.12 mM); Clear solution |
| Appearance | Light yellow to yellow (Solid) |
| Storage | Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month |
| Complexity | 561 |
| Exact Mass | 408.02600 |
| PSA | 104.16000 |
| Target | HCV |
| XLogP3-AA | 3.1 |