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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
AL-470
![{PARAM:[Name]}()](https://resource.bocsci.com/structure/2671019-15-9.gif)
| Category | Human immunodeficiency Virus (HIV) |
| CAS | 2671019-15-9 |
| Description | AL-470 is a potent antiviral agent with EC50 values of 0.27, 0.63, and 0.35 µM against HIV-1, HIV-2, and EV-A71, respectively. |
Product Information
| Synonyms | AL-470|HY-146009|CS-0460334 |
| Molecular Weight | 1328.2 |
| Molecular Formula | C67H57N7O23 |
| Canonical SMILES | C1=CC=C2C(=C1)C(=C(N2)C3=CC(=CC(=C3)C(=O)O)C(=O)O)CC(C(=O)O)NC(=O)CCC(CCC(=O)NC(CC4=C(NC5=CC=CC=C54)C6=CC(=CC(=C6)C(=O)O)C(=O)O)C(=O)O)(CCC(=O)NC(CC7=C(NC8=CC=CC=C87)C9=CC(=CC(=C9)C(=O)O)C(=O)O)C(=O)O)[N+](=O)[O-] |
| Purity | >99% |
| Solubility | DMSO: 64 mg/mL |
| Appearance | Solid powder |
| Storage | Solid powder: -20 °C refrigerated long-term storage |
| Complexity | 2600 |
| Exact Mass | 1327.35058109 |
| In Vivo | The entire panel of AL-470 against the mutant EV-A71 strain shows antiviral activity: EV-A71 BrCr wt (EC50=0.3±0.03 μM), VP1\U S184T (EC50=2.3±0.6μM), VP1\U P246S (EC50=1.9±0.04μM), VP1\U S184T\U P246S (EC50=2.2±0.08μM). |
| Target | HIV-1:0.27 μM (EC50) HIV-2:0.63 μM (EC50) EV-A71:0.35 μM (EC50) |
| XLogP3-AA | 6 |
