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Antiviral API
- Arenavirus
- Cytomegalovirus (CMV)
- Endogenous Metabolite
- Enterovirus (EV)
- Epstein-Barr virus (EBV)
- Filovirus
- HCV Protease
- Hepatitis B Virus (HBV)
- Hepatitis C Virus (HCV)
- Herpes simplex Virus (HSV)
- HIF/HIF Prolyl-Hydroxylase
- HIV Integrase
- HIV Protease
- Human immunodeficiency Virus (HIV)
- Human papillomavirus (HPV)
- Influenza Virus
- Orthopoxvirus
- Others
- Respiratory syncytial Virus (RSV)
- Reverse Transcriptases (RTs)
- SARS-CoV
- Virus Protease
- Antiviral intermediates
AIC-292
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| Category | Human immunodeficiency Virus (HIV) |
| CAS | 1187917-12-9 |
| Description | AIC-292 is a potent and selective inhibitor of HIV-1 nonnucleoside reverse transcriptase. It inhibits wild-type HIV-1 laboratory strains at low nanomolar concentrations. AIC-292 displays potent antiviral in vivo efficacy in a mouse xenograft model. |
Product Information
| Synonyms | AIC-292|LE2GYT0UFH|UNII-LE2GYT0UFH|1187917-12-9|AIC292|SCHEMBL1526038|AIC 292|SB17103|HY-19925|CS-0016931|1-((1-(3-Chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazol-3-yl)carbonyl)-4-imidazolidinone|1-[1-(3-chloro-4-fluoro-phenyl)-5-(3-chloro-5-fluoro-phenyl)pyrazole-3-carbonyl]imidazolidin-4-one|1-{[1-(3-Chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazol-3-yl]carbonyl}imidazolidin-4-one|4-Imidazolidinone, 1-((1-(3-chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)-1H-pyrazol-3-yl)carbonyl)- |
| Molecular Weight | 437.23 |
| Molecular Formula | C19H12Cl2F2N4O2 |
| Canonical SMILES | C1C(=O)NCN1C(=O)C2=NN(C(=C2)C3=CC(=CC(=C3)Cl)F)C4=CC(=C(C=C4)F)Cl |
| Purity | ≥95% |
| Solubility | In vitro: 10 mM in DMSO |
| Appearance | A crystalline solid |
| Storage | -20°C |
| Complexity | 645 |
| Exact Mass | 436.0305374 |
| Target | HIV |
| XLogP3-AA | 4 |
